Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72340 | 0.97 | LMNA (0.64) | LMNAF2TSHRALDH1A1MAPT | |
| SCHEMBL9138584 | 0.95 | LMNA (0.61) | LMNAF2TSHRALDH1A1MAPT | |
| SCHEMBL27515576 | 0.95 | LMNA (0.61) | LMNAF2TSHRALDH1A1MAPT | |
| SCHEMBL27754069 | 0.95 | LMNA (0.61) | LMNAF2TSHRALDH1A1MAPT | |
| SCHEMBL29171336 | 0.95 | LMNA (0.61) | LMNAF2TSHRALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5413799 | 0.95 | LMNA (0.61) | LMNAF2TSHRALDH1A1MAPT | |
| SCHEMBL27540356 | 0.95 | LMNA (0.61) | LMNAF2TSHRALDH1A1MAPT | |
| SCHEMBL27153766 | 0.95 | LMNA (0.61) | LMNAF2TSHRALDH1A1MAPT | |
| SCHEMBL21585876 | 0.95 | LMNA (0.61) | LMNAF2TSHRALDH1A1MAPT | |
| Phosphine SCHEMBL27690054 | 0.95 | LMNA (0.61) | LMNAF2TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347689-B1 | PROCESS FOR THE PREPARATION OF N-HYDROXYPYRAZOLES | BASF Aktiengesellschaft (DE) | 1993-09-22 | — | — | EP | disclosed |
| EP-0347676-B1 | PROCESS FOR THE PREPARATION OF N-HYDROXYPYRAZOLES | BASF Aktiengesellschaft (DE) | 1993-09-15 | — | — | EP | disclosed |
| EP-0347676-A1 | Process for the preparation of N-hydroxypyrazoles | BASF Aktiengesellschaft (DE) | 1989-12-27 | — | — | EP | disclosed |
| EP-0347689-A1 | Process for the preparation of N-hydroxypyrazoles | BASF Aktiengesellschaft (DE) | 1989-12-27 | — | — | EP | disclosed |