SCHEMBL9520504

SCHEMBL9520504

CCc1cn2ccnc2s1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TLR8 Q9NR97 2/20 0.31
KEAP1 Q14145 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14639026 0.80 HDAC1 (0.34) HDAC1HDAC2KEAP1
SCHEMBL14639027 0.80 HDAC1 (0.34) HDAC1HDAC2KEAP1
SCHEMBL3722925 0.74 HDAC1 (0.39) HDAC1HDAC2KEAP1L3MBTL1
SCHEMBL2054430 0.72
SCHEMBL6525101 0.69 ALDH1A1 (0.33) SMN1; SMN2ALDH1A1
SCHEMBL23535638 0.68
SCHEMBL5048959 0.68
SCHEMBL5045826 0.68
SCHEMBL13676589 0.68 TNKS (0.32) HDAC1HDAC2L3MBTL1
SCHEMBL11129279 0.68 KDM4E (0.38) SMN1; SMN2ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0238070-B1 Sulfonylurea compounds, their production and herbicidal use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-29 EP disclosed
US-5017212-A For rice paddies TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US disclosed
EP-0238070-A2 Sulfonylurea compounds, their production and herbicidal use Takeda Chemical Industries, Ltd. (JP) 1987-09-23 EP disclosed