Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752193 | 0.83 | NPC1 (0.49) | NPC1RAB9APKMKDM4ESMN1; SMN2 | |
| SCHEMBL11538222 | 0.82 | NPC1 (0.64) | NPC1RAB9APKMKDM4ESMN1; SMN2 | |
| SCHEMBL9521512 | 0.81 | RAB9A (0.58) | NPC1RAB9APKMKDM4ESMN1; SMN2 | |
| SCHEMBL9521647 | 0.76 | NPC1 (0.49) | NPC1RAB9APKMKDM4ESMN1; SMN2 | |
| SCHEMBL6179239 | 0.73 | NPC1 (0.60) | NPC1RAB9APKMKDM4ESMN1; SMN2 | |
| SCHEMBL29655094 | 0.73 | NPC1 (0.60) | NPC1RAB9APKMKDM4ESMN1; SMN2 | |
| SCHEMBL10782202 | 0.73 | NPC1 (0.54) | NPC1RAB9APKMKDM4ESMN1; SMN2 | |
| SCHEMBL11539536 | 0.72 | NPC1 (0.62) | NPC1RAB9APKMKDM4ESMN1; SMN2 | |
| SCHEMBL9521601 | 0.72 | MAPT (0.45) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8752167 | 0.72 | RAB9A (0.46) | NPC1RAB9APKMKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366614-B1 | PHARMACEUTICALLY ACTIVE DITHIOKETENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1993-09-01 | — | — | EP | disclosed |
| US-5103013-A | For treating liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-04-07 | — | — | US | disclosed |
| EP-0366614-A2 | Pharmaceutically active dithioketene derivatives | YUHAN CORPORATION, LTD. (KR) | 1990-05-02 | — | — | EP | disclosed |