Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 15/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520739 | 1.00 | CHRM5 (0.43) | CHRM5NPY5RTDP1GAATSHR | |
| SCHEMBL9521328 | 0.85 | CHRM5 (0.46) | CHRM5NPY5RTDP1GAATSHR | |
| SCHEMBL9520022 | 0.85 | CHRM5 (0.45) | CHRM5NPY5RTDP1GAATSHR | |
| SCHEMBL9520031 | 0.85 | CHRM5 (0.45) | CHRM5NPY5RTDP1GAATSHR | |
| SCHEMBL9521025 | 0.85 | CHRM5 (0.44) | CHRM5NPY5RTDP1GAATSHR | |
| SCHEMBL9519676 | 0.84 | CHRM5 (0.46) | CHRM5NPY5RTDP1GAATSHR | |
| SCHEMBL9519974 | 0.82 | TDP1 (0.51) | CHRM5NPY5RTDP1GAATSHR | |
| SCHEMBL9519555 | 0.81 | NPY5R (0.51) | NPY5R | |
| SCHEMBL9522608 | 0.81 | NPY5R (0.60) | NPY5R | |
| SCHEMBL9519550 | 0.81 | NPY5R (0.51) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288973-B1 | BENZOTHIAZOLINONE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION | Fujisawa Astra Ltd. (JP) | 1993-01-13 | — | — | EP | disclosed |
| US-4879301-A | Antiallergic and antiinflammatory benzothiazolinone derivatives | HOEI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0288973-A2 | Benzothiazolinone derivatives, their production and pharmaceutical composition | Fujisawa Astra Ltd. (JP) | 1988-11-02 | — | — | EP | disclosed |