Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 13/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521328 | 0.86 | CHRM5 (0.46) | TDP1CHRM5GAATSHRNPSR1 | |
| SCHEMBL9519651 | 0.86 | NPY5R (0.44) | TDP1CHRM5GAATSHRNPSR1 | |
| SCHEMBL9522896 | 0.86 | TDP1 (0.52) | TDP1CHRM5GAATSHRNPSR1 | |
| SCHEMBL9521025 | 0.86 | CHRM5 (0.44) | TDP1CHRM5GAATSHRNPSR1 | |
| SCHEMBL9519676 | 0.83 | CHRM5 (0.46) | TDP1CHRM5GAATSHRNPSR1 | |
| SCHEMBL9520751 | 0.82 | CHRM5 (0.43) | TDP1CHRM5GAATSHRNPSR1 | |
| SCHEMBL9520739 | 0.82 | CHRM5 (0.43) | TDP1CHRM5GAATSHRNPSR1 | |
| SCHEMBL9519675 | 0.81 | NPY5R (0.59) | TDP1NPY5R | |
| SCHEMBL9521617 | 0.81 | TDP1 (0.53) | TDP1GAATSHRNPSR1NPY5R | |
| SCHEMBL145367 | 0.77 | ALDH1A1 (0.48) | TDP1GAATSHRNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288973-B1 | BENZOTHIAZOLINONE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION | Fujisawa Astra Ltd. (JP) | 1993-01-13 | — | — | EP | disclosed |
| US-4879301-A | Antiallergic and antiinflammatory benzothiazolinone derivatives | HOEI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0288973-A2 | Benzothiazolinone derivatives, their production and pharmaceutical composition | Fujisawa Astra Ltd. (JP) | 1988-11-02 | — | — | EP | disclosed |