Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520763 | 1.00 | ALDH1A1 (0.33) | ALDH1A1FFAR3TSHRTDP1LMNA | |
| SCHEMBL28421065 | 0.83 | FFAR3 (0.37) | ALDH1A1FFAR3TSHRLMNAHSD17B10 | |
| SCHEMBL18092840 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1LMNAHSD17B10 | |
| SCHEMBL370148 | 0.79 | MGAM (0.41) | ALDH1A1TDP1 | |
| SCHEMBL28238687 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TSHRLMNAHSD17B10 | |
| SCHEMBL9259007 | 0.76 | — | — | |
| SCHEMBL7869619 | 0.75 | — | — | |
| SCHEMBL7869622 | 0.75 | — | — | |
| SCHEMBL3555075 | 0.74 | FFAR3 (0.35) | ALDH1A1FFAR3TSHRGRIK1GRIK2 | |
| SCHEMBL27044 | 0.74 | FFAR3 (0.35) | ALDH1A1FFAR3TSHRGRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216141-A | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR LINKAGES | BENNER, STEVEN | 1993-06-01 | — | — | US | disclosed |
| EP-0418309-A4 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | — | 1993-01-07 | — | — | EP | disclosed |
| EP-0418309-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER, Steven Albert (CH) | 1991-03-27 | — | — | EP | disclosed |
| WO-1989012060-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER STEVEN ALBERT (CH) | 1989-12-14 | — | — | WO | disclosed |