Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GRM5 | P41594 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521754 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AGLAHTT | |
| SCHEMBL13966673 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AGLAHTT | |
| SCHEMBL9521570 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AGLAHTT | |
| SCHEMBL21348216 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AGLAHTT | |
| SCHEMBL9522671 | 0.75 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AGLAHTT | |
| SCHEMBL13942148 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AGLAHTT | |
| SCHEMBL14970141 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AGLAHTT | |
| SCHEMBL558521 | 0.70 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AGLAHTT | |
| SCHEMBL558564 | 0.70 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AGLAHTT | |
| SCHEMBL18809728 | 0.70 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AGLAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257850-B1 | Pyrimidine derivatives | NISSIN FOOD PRODUCTS LTD (JP) | 1993-12-08 | — | — | EP | claimed |
| EP-0559742-A1 | HERBICIDAL OXAZINE ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-15 | — | — | EP | claimed |
| US-4849424-A | ANTIULCER AGENTS | NISSIN SHOKUHIN KABUSHIKI KAISHA (JP) | 1989-07-18 | — | — | US | claimed |
| EP-0257850-A2 | Pyrimidine derivatives | NISSIN SHOKUHIN KABUSHIKI KAISHA doing international business as NISSIN FOOD PRODUCTS CO., LTD. (JP) | 1988-03-02 | — | — | EP | claimed |
| EP-0257850-B1 | Pyrimidine derivatives | NISSIN FOOD PRODUCTS LTD (JP) | 1993-12-08 | — | — | EP | disclosed |
| EP-0559742-A1 | HERBICIDAL OXAZINE ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| EP-0525106-A4 | 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0525106-A1 | 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4849424-A | ANTIULCER AGENTS | NISSIN SHOKUHIN KABUSHIKI KAISHA (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0257850-A2 | Pyrimidine derivatives | NISSIN SHOKUHIN KABUSHIKI KAISHA doing international business as NISSIN FOOD PRODUCTS CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |