Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 6/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521754 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AGLAALDH1A1 | |
| SCHEMBL10672705 | 0.78 | NPC1 (0.63) | SMN1; SMN2NPC1RAB9AGLAALDH1A1 | |
| SCHEMBL9521570 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AGLAALDH1A1 | |
| SCHEMBL16210934 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AGLAALDH1A1 | |
| SCHEMBL13966673 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AGLAALDH1A1 | |
| SCHEMBL8217612 | 0.75 | SMN1; SMN2 (0.71) | SMN1; SMN2NPC1RAB9AGLAALDH1A1 | |
| SCHEMBL9520837 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AGLAALDH1A1 | |
| SCHEMBL30212531 | 0.73 | NPC1 (0.57) | SMN1; SMN2NPC1RAB9AGLAALDH1A1 | |
| SCHEMBL7096815 | 0.72 | NPC1 (0.56) | SMN1; SMN2NPC1RAB9AGLAALDH1A1 | |
| SCHEMBL13942148 | 0.70 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257850-B1 | Pyrimidine derivatives | NISSIN FOOD PRODUCTS LTD (JP) | 1993-12-08 | — | — | EP | claimed |
| US-4849424-A | ANTIULCER AGENTS | NISSIN SHOKUHIN KABUSHIKI KAISHA (JP) | 1989-07-18 | — | — | US | claimed |
| EP-0257850-B1 | Pyrimidine derivatives | NISSIN FOOD PRODUCTS LTD (JP) | 1993-12-08 | — | — | EP | disclosed |
| EP-0546108-A4 | PRO-DRUGS FOR CCK ANTAGONISTS | — | 1993-09-22 | — | — | EP | disclosed |
| EP-0546108-A1 | PRO-DRUGS FOR CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| US-4849424-A | ANTIULCER AGENTS | NISSIN SHOKUHIN KABUSHIKI KAISHA (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0257850-A2 | Pyrimidine derivatives | NISSIN SHOKUHIN KABUSHIKI KAISHA doing international business as NISSIN FOOD PRODUCTS CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |