Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922233 | 0.85 | ALDH1A1 (0.38) | CCR5ALDH1A1MAPTHPGDOPRK1 | |
| SCHEMBL8691844 | 0.85 | ALDH1A1 (0.38) | CCR5ALDH1A1MAPTHPGDOPRK1 | |
| SCHEMBL9519325 | 0.85 | ALDH1A1 (0.38) | CCR5ALDH1A1MAPTHPGDOPRK1 | |
| SCHEMBL8923969 | 0.85 | ALDH1A1 (0.37) | CCR5ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8693099 | 0.85 | ALDH1A1 (0.37) | CCR5ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8923324 | 0.84 | ALDH1A1 (0.40) | CCR5ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8689878 | 0.84 | ALDH1A1 (0.40) | CCR5ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9366344 | 0.84 | ALDH1A1 (0.40) | CCR5ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9369560 | 0.84 | ALDH1A1 (0.40) | CCR5ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8925961 | 0.84 | ALDH1A1 (0.40) | CCR5ALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280771-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5061804-A | 3-thiopyrrolidine as chemical intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |