SCHEMBL95211

SCHEMBL95211

O=Cc1cccc(Cl)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
TDP1 Q9NUW8 3/20 0.54
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
LMNA P02545 3/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
PPP1R15A O75807 1/20 0.46
MELK Q14680 1/20 0.46
PPP1R15B Q5SWA1 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ERN1 O75460 2/20 0.43
TSHR P16473 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
TRIM24 O15164 1/20 0.41
TRIM33 Q9UPN9 1/20 0.41
PTGS2 P35354 1/20 0.40
DYRK1A Q13627 1/20 0.40
PNMT P11086 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30011286 1.00 ALDH1A1 (0.54) ALDH1A1TDP1KMT2AMEN1LMNA
Hydrochloric Acid SCHEMBL28994838 0.98 ALDH1A1 (0.52) ALDH1A1TDP1KMT2AMEN1LMNA
Hydrochloric Acid SCHEMBL29009133 0.98 ALDH1A1 (0.52) ALDH1A1TDP1KMT2AMEN1LMNA
Methylene Chloride SCHEMBL28779667 0.93 ALDH1A1 (0.48) ALDH1A1TDP1KMT2AMEN1LMNA
SCHEMBL3794351 0.87 TDP1 (0.58) ALDH1A1TDP1KMT2AMEN1LMNA
SCHEMBL7009789 0.83 ALDH1A1 (0.53) ALDH1A1TDP1KMT2AMEN1LMNA
SCHEMBL30234436 0.81 ALDH1A1 (0.50) ALDH1A1TDP1KMT2AMEN1LMNA
SCHEMBL2475165 0.81 ALDH1A1 (0.50) ALDH1A1TDP1KMT2AMEN1LMNA
SCHEMBL19960372 0.81 TDP1 (0.46) ALDH1A1TDP1KMT2AMEN1LMNA
SCHEMBL10533687 0.81 TDP1 (0.46) ALDH1A1TDP1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3054 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118903471-B Sodium pyruvate sustained-release nano preparation based on pH response and preparation method and application thereof 江苏长泰药业股份有限公司 2025-01-17 CN claimed
CN-119081040-A Preparation method of chemically recyclable polyacetal and product and chemical recycling method thereof 浙江大学 2024-12-06 CN claimed
CN-118903471-A Sodium pyruvate sustained-release nano-carrier based on pH response and preparation method and application thereof 江苏长泰药业股份有限公司 2024-11-08 CN claimed
CN-118852032-A Alpha, beta-unsaturated ketone derivative, preparation method and application thereof 赣南医科大学 2024-10-29 CN claimed
CN-118496215-A Polyhydroxylated onium derivative with disubstituted benzene ring, preparation method and medical application thereof 中国药科大学 2024-08-16 CN claimed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-117624148-A Polyhydroxy sulfonium salt derivative with disubstituted benzene ring, preparation method and medical application thereof 中国药科大学 2024-03-01 CN claimed
US-20240033318-A1 PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION OHIO STATE INNOVATION FOUNDATION 2024-02-01 US claimed
CN-113620919-B Mechanical ball milling assisted synthesis method of 2-amino-3-cyano-4H-pyran compound 浙江工业大学 2023-12-12 CN claimed
US-5191126-A PROCESS FOR THE PREPARATION OF DIFLUOROBENZALDEHYDES HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-02 US claimed
EP-0523668-A2 Process for the preparation of difluorobenzaldehydes HOECHST AKTIENGESELLSCHAFT (DE) 1993-01-20 EP claimed
EP-0207732-B1 PLATING BATH AND METHOD FOR ELECTROPLATING TIN AND/OR LEAD MCGEAN-ROHCO, INC. (US) 1992-02-12 EP claimed
EP-0311053-A2 Ameliorant of cerebral circulation and optical isomer of nb-818, processes for its production and its use BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-04-12 EP claimed
US-4662999-A Plating bath and method for electroplating tin and/or lead MCGEAN-ROHCO, INC. (US) 1987-05-05 US claimed
EP-0207732-A1 Plating bath and method for electroplating tin and/or lead MCGEAN-ROHCO, INC. (US) 1987-01-07 EP claimed
EP-0007293-B1 2,6-DIMETHYL-4-(2,3-DICHLOROPHENYL)-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID-3-METHYL ESTER-5-ETHYL ESTER HAVING HYPOTENSIVE PROPERTIES, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING IT Aktiebolaget Hässle (SE) 1982-06-23 EP claimed
US-4135991-A BATH AND METHOD FOR ELECTROPLATING TIN AND/OR LEAD R. O. HULL & COMPANY, INC. (US) 1979-01-23 US claimed
US-4136122-A SEPARATION OF 2,6-DICHLOROBENZALDEHYDE FROM ISOMERIC MIXTURES HOOKER CHEMICALS & PLASTICS CORP. (US) 1979-01-23 US claimed
US-4000047-A PYRIDINE OR QUINOLINE COMPOUND BRIGHTENERS LEA-RONAL, INC. (US) 1976-12-28 US claimed