Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.46 |
| ▸ | GSK3A | P49840 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | RGS4 | P49798 | 1/20 | 0.38 |
| ▸ | RGS8 | P57771 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519526 | 0.73 | GSK3B (0.51) | GSK3BGSK3ARGS4RGS8 | |
| SCHEMBL9519955 | 0.66 | POLB (0.43) | GSK3BGSK3AGAAPOLBALDH1A1 | |
| SCHEMBL10392954 | 0.64 | GSK3B (0.44) | GSK3BGSK3AGAAPOLBALDH1A1 | |
| SCHEMBL10392953 | 0.64 | GSK3B (0.44) | GSK3BGSK3AGAAPOLBALDH1A1 | |
| SCHEMBL23642992 | 0.64 | GSK3B (1.00) | GSK3BGSK3AGAAALDH1A1MEN1 | |
| SCHEMBL9521107 | 0.61 | GSK3B (0.41) | GSK3BGSK3AGAAPOLBALDH1A1 | |
| SCHEMBL18925442 | 0.61 | GSK3A (0.50) | GSK3BGSK3AGAAALDH1A1NOTUM | |
| SCHEMBL23642988 | 0.61 | GSK3A (0.59) | GSK3BGSK3AALDH1A1 | |
| SCHEMBL1722780 | 0.60 | GSK3B (0.71) | GSK3BGSK3AGAAALDH1A1MEN1 | |
| SCHEMBL5306506 | 0.60 | MAPK1 (0.71) | GSK3BGSK3AGAAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300898-B1 | PYRETHRINOID DERIVATIVES CONTAINING AN N-HETEROCYCLE, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-03-10 | — | — | EP | disclosed |