Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 5/20 | 0.42 |
| ▸ | GSK3A | P49840 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10392954 | 0.78 | GSK3B (0.44) | POLBSMN1; SMN2MAPTNOTUMGSK3B | |
| SCHEMBL10392953 | 0.78 | GSK3B (0.44) | POLBSMN1; SMN2MAPTNOTUMGSK3B | |
| SCHEMBL9521107 | 0.77 | GSK3B (0.41) | POLBSMN1; SMN2MAPTNOTUMGSK3B | |
| SCHEMBL9868309 | 0.75 | KDM4E (0.47) | MAPTNOTUMGSK3BGSK3AKMT2A | |
| SCHEMBL9521154 | 0.66 | GSK3B (0.46) | POLBSMN1; SMN2NOTUMGSK3BGSK3A | |
| SCHEMBL11396889 | 0.65 | ALDH1A1 (0.55) | POLBSMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL9521586 | 0.65 | CYP3A4 (0.36) | POLBSMN1; SMN2ALDH1A1KDM4ERAB9A | |
| SCHEMBL9522954 | 0.65 | — | — | |
| SCHEMBL9519978 | 0.64 | NOTUM (0.36) | POLBNOTUMALDH1A1 | |
| SCHEMBL3050974 | 0.64 | NOTUM (0.57) | POLBSMN1; SMN2MAPTNOTUMGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300898-B1 | PYRETHRINOID DERIVATIVES CONTAINING AN N-HETEROCYCLE, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-03-10 | — | — | EP | disclosed |
| EP-0300898-A1 | Pyrethrinoid derivatives containing an N-heterocycle, processes and intermediates for their preparation, their use as pesticides and compositions containing them | ROUSSEL-UCLAF (FR) | 1989-01-25 | — | — | EP | disclosed |