Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11952830 | 0.79 | ALDH1A1 (0.41) | MEN1KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL867976 | 0.79 | TDP1 (0.41) | MEN1KMT2ACYP2C19TDP1 | |
| Hydrochloric Acid SCHEMBL5577032 | 0.77 | TDP1 (0.39) | CYP2C19TDP1 | |
| SCHEMBL1594292 | 0.77 | MEN1 (0.32) | MEN1KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL13138710 | 0.77 | MEN1 (0.32) | MEN1KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL27737217 | 0.75 | MEN1 (0.31) | MEN1KMT2ACYP2C19ALDH1A1TDP1 | |
| SCHEMBL12988839 | 0.75 | TDP1 (0.45) | MEN1KMT2AALDH1A1TDP1 | |
| Bicarbonate SCHEMBL27506741 | 0.73 | FFAR3 (0.35) | MEN1KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL22592155 | 0.73 | TSHR (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9579552 | 0.71 | MEN1 (0.36) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226896-B1 | LANKACIDIN DERIVATIVES AND PRODUCTION THEREOF | Takeda Chemical Industries, Ltd. (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |