Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.58 |
| ▸ | CDK8 | P49336 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9839090 | 0.98 | CCNC (0.57) | CCNCCDK8KMT2ALMNAALOX15 | |
| SCHEMBL6209531 | 0.84 | KMT2A (0.65) | CCNCCDK8KMT2ALMNAFAAH | |
| SCHEMBL12150066 | 0.84 | CCNC (0.53) | CCNCCDK8KMT2ALMNAALOX15 | |
| SCHEMBL6294601 | 0.84 | KMT2A (0.57) | CCNCCDK8KMT2ALMNAALOX15 | |
| SCHEMBL11200179 | 0.82 | KMT2A (0.48) | CCNCCDK8KMT2AALOX15FAAH | |
| SCHEMBL28000128 | 0.81 | CCNC (0.50) | CCNCCDK8KMT2ALMNAALOX15 | |
| SCHEMBL9002813 | 0.81 | KMT2A (0.59) | CCNCCDK8KMT2AALOX15FAAH | |
| SCHEMBL6213582 | 0.80 | KMT2A (0.64) | CCNCCDK8KMT2ALMNAALDH1A1 | |
| SCHEMBL29473371 | 0.79 | CCNC (0.57) | CCNCCDK8KMT2ALMNAALOX15 | |
| SCHEMBL4059898 | 0.79 | CCNC (0.57) | CCNCCDK8KMT2ALMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302253-B1 | 3-DEMETHYL-4-FLUORO-MEVALONIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS BASED ON THOSE COMPOUNDS, THEIR USE AND INTERMEDIATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-07 | — | — | EP | disclosed |
| EP-0281789-B1 | BENZYLAMINOARYLDIHYDROPYRIDINE LACTONES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICAMENTS | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |
| EP-0302253-A1 | 3-Demethyl-4-fluoro-mevalonic-acid derivatives, process for their preparation, pharmaceutical preparations based on those compounds, their use and intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-08 | — | — | EP | disclosed |
| EP-0157324-B1 | TETRAHYDROTHIENOPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL APPLICATION | BAYER AG (DE) | 1988-08-31 | — | — | EP | disclosed |
| EP-0234517-A1 | Pyrrolo[3,4-b]pyridines, process for their preparation and medicaments containing them for the treatment of vascular diseases | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1987-09-02 | — | — | EP | disclosed |
| EP-0202436-A2 | Process for dyeing or printing cellulosic fibres or cellulosic mixed fibres | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-11-26 | — | — | EP | disclosed |
| EP-0123095-A2 | Chromone- and thiochromone-substited 1,4-dihydropyridine lactones, processes for their preparation and their use as pharmaceutical preparations | BAYER AG (DE) | 1984-10-31 | — | — | EP | disclosed |