Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652565 | 0.85 | CETP (0.44) | TSHRKDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10346735 | 0.85 | CETP (0.44) | TSHRKDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9521927 | 0.81 | TSHR (0.47) | TSHRKDM4EPOLBARALDH1A1 | |
| SCHEMBL4889465 | 0.81 | TSHR (0.50) | TSHRKDM4EPOLBARALDH1A1 | |
| SCHEMBL18526730 | 0.78 | KDM4E (0.53) | TSHRKDM4EPOLBARALDH1A1 | |
| SCHEMBL28173813 | 0.78 | TSHR (0.47) | TSHRKDM4EPOLBARALDH1A1 | |
| SCHEMBL6792841 | 0.77 | SLC6A2 (0.47) | ALDH1A1SMN1; SMN2RIPK1TAAR1 | |
| SCHEMBL19621150 | 0.77 | TSHR (0.54) | TSHRKDM4EPOLBALDH1A1TACR1 | |
| SCHEMBL14317668 | 0.77 | TSHR (0.54) | TSHRKDM4EPOLBALDH1A1TACR1 | |
| SCHEMBL13888734 | 0.75 | KDM4E (0.46) | TSHRKDM4EPOLBARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211598-B1 | Pesticidal compounds | WELLCOME FOUND (GB) | 1993-12-15 | — | — | EP | disclosed |
| US-5098929-A | Insecticides, insect attractants, fungicides or oxidase inhibitors | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-03-24 | — | — | US | disclosed |
| EP-0211598-A2 | Pesticidal compounds | ROUSSEL-UCLAF (FR) | 1987-02-25 | — | — | EP | disclosed |