Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522007 | 1.00 | CES2 (0.47) | CES2CES1ALDH1A1HTTMAPK14 | |
| SCHEMBL7475182 | 0.83 | CES2 (0.48) | CES2CES1ALDH1A1HTTMAPK14 | |
| SCHEMBL9521302 | 0.83 | CES2 (0.48) | CES2CES1ALDH1A1HTTMAPK14 | |
| SCHEMBL7481905 | 0.83 | CES2 (0.48) | CES2CES1ALDH1A1HTTMAPK14 | |
| SCHEMBL9522760 | 0.78 | CES2 (0.57) | CES2CES1ALDH1A1HTTMAPK14 | |
| SCHEMBL6939794 | 0.78 | CES2 (0.57) | CES2CES1ALDH1A1HTTMAPK14 | |
| SCHEMBL29727310 | 0.74 | CES2 (0.56) | CES2CES1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL13689710 | 0.74 | CES2 (0.56) | CES2CES1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL10363839 | 0.71 | CES2 (0.58) | CES2CES1ALDH1A1HTTNPC1 | |
| SCHEMBL16560497 | 0.71 | CES2 (0.58) | CES2CES1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332387-B1 | Triazole derivatives, their preparation and their use as fungicides | SANKYO CO (JP) | 1993-11-24 | — | — | EP | disclosed |
| EP-0332387-A1 | Triazole derivatives, their preparation and their use as fungicides | Sankyo Company Limited (JP) | 1989-09-13 | — | — | EP | disclosed |