SCHEMBL9523164

CC(C)[C@H](NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CNC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)CN)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.54

▸	NPY4R	P50391	13/20	0.53

▸	NPY5R	Q15761	9/20	0.53

▸	NPY1R	P25929	8/20	0.53

▸	NPY2R	P49146	6/20	0.53

▸	IL23R	Q5VWK5	5/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9522231	0.91	NPY4R (0.51)	NPY4RNPY5RNPY1RNPY2R
SCHEMBL5049208	0.88	NPY4R (0.59)	TFPINPY4RNPY5RNPY1RNPY2R
SCHEMBL15092950	0.88	NPY4R (0.54)	NPY4RNPY5RNPY1RNPY2R
SCHEMBL15092953	0.88	NPY4R (0.54)	NPY4RNPY5RNPY1RNPY2R
SCHEMBL16348162	0.87	TFPI (0.60)	TFPINPY4RNPY5RNPY1RNPY2R
SCHEMBL21481072	0.87	NPY4R (0.59)	NPY4RNPY5RNPY1RNPY2R
SCHEMBL29391074	0.87	NPY4R (0.59)	NPY4RNPY5RNPY1RNPY2R
SCHEMBL30521958	0.87	NPY4R (0.53)	TFPINPY4RNPY5RNPY1RNPY2R
SCHEMBL12589785	0.87	TFPI (0.64)	TFPINPY4RNPY5RNPY1RNPY2R
SCHEMBL12589782	0.87	TFPI (0.64)	TFPINPY4RNPY5RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0527189-A1	NOVEL CC-1065 ANALOGS	PHARMACIA & UPJOHN COMPANY (US)	1993-02-17	—	—	EP	claimed