Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | CHRNG | P07510 | 2/20 | 0.38 |
| ▸ | CHRND | Q07001 | 2/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 2/20 | 0.30 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521417 | 0.92 | SLC6A4 (0.36) | SLC6A4SLC6A3CHRNA1CHRNB1CHRNB2 | |
| SCHEMBL9641402 | 0.88 | SLC6A3 (0.39) | SLC6A4SLC6A3CHRNA1CHRNB1CHRNB2 | |
| SCHEMBL9521920 | 0.87 | TAAR1 (0.31) | — | |
| SCHEMBL9522108 | 0.87 | SLC5A1 (0.31) | — | |
| SCHEMBL9522026 | 0.83 | — | — | |
| SCHEMBL9521956 | 0.82 | SLC6A3 (0.38) | SLC6A4SLC6A3CHRNA1CHRNB1CHRNB2 | |
| SCHEMBL9522318 | 0.81 | CHRNA1 (0.32) | SLC6A4SLC6A3CHRNA1CHRNB1CHRNB2 | |
| SCHEMBL9522006 | 0.80 | — | — | |
| SCHEMBL9522134 | 0.79 | CNR1 (0.32) | — | |
| SCHEMBL9523082 | 0.79 | CNR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211598-B1 | Pesticidal compounds | WELLCOME FOUND (GB) | 1993-12-15 | — | — | EP | claimed |
| EP-0211598-A2 | Pesticidal compounds | ROUSSEL-UCLAF (FR) | 1987-02-25 | — | — | EP | claimed |
| US-5098929-A | Insecticides, insect attractants, fungicides or oxidase inhibitors | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-03-24 | — | — | US | disclosed |
| EP-0211598-A2 | Pesticidal compounds | ROUSSEL-UCLAF (FR) | 1987-02-25 | — | — | EP | disclosed |