SCHEMBL9522735

SCHEMBL9522735

O=C1C=CC2=C(C1)C(=O)OC2=O.O=C1C=CC2=C(C1)C(=O)OC2=O

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.43
GSK3B P49841 1/20 0.43
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10513930 1.00 GSK3A (0.43) GSK3AGSK3BTRPA1
SCHEMBL2831188 0.78 TRPA1 (0.32) TRPA1
SCHEMBL29239508 0.71
SCHEMBL4788434 0.70 TRPA1 (0.39) TRPA1
SCHEMBL30312960 0.67 GSK3A (0.42) GSK3AGSK3B
SCHEMBL9435710 0.67 GSK3A (0.42) GSK3AGSK3B
SCHEMBL1872402 0.67 TRPA1 (0.54) TRPA1
SCHEMBL31565114 0.66
SCHEMBL3400665 0.65
SCHEMBL277815 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0314766-B1 METHOD FOR MAKING THIANTHRENE DIANHYDRIDE AND POLYIMIDES OBTAINED THEREFROM GEN ELECTRIC (US) 1993-11-03 EP disclosed
US-4864015-A OXIDATION RESISTANT COMPOSITES GENERAL ELECTRIC COMPANY (US) 1989-09-05 US disclosed
EP-0314766-A1 METHOD FOR MAKING THIANTHRENE DIANHYDRIDE AND POLYIMIDES OBTAINED THEREFROM. GEN ELECTRIC (US) 1989-05-10 EP disclosed
US-4814466-A FORMING A BISIMIDE FROM AN ALKALI SULFIDE AND AN N-ORGANO-4,5-DIHALOPHTHALIMIDE; HYDROLYSIS AND DEHYDRATION GENERAL ELECTRIC COMPANY (US) 1989-03-21 US disclosed
WO-1988009353-A1 METHOD FOR MAKING THIANTHRENE DIANHYDRIDE AND POLYIMIDES OBTAINED THEREFROM GENERAL ELECTRIC COMPANY (US) 1988-12-01 WO disclosed