Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959264 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL27738196 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9524635 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30114672 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1031955 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4819062 | 0.84 | HPGD (0.48) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1030553 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4987555 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8421994 | 0.83 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7010374 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523067-A1 | CROP-SELECTIVE HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-20 | — | — | EP | disclosed |