Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP4 | P49662 | 1/20 | 0.43 |
| ▸ | CASP5 | P51878 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522974 | 1.00 | NFKB1 (0.58) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9521708 | 0.83 | NFKB1 (0.44) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9522658 | 0.83 | NFKB1 (0.44) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9521715 | 0.83 | NFKB1 (0.44) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9521812 | 0.83 | NFKB1 (0.59) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9521808 | 0.83 | NFKB1 (0.59) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL9521818 | 0.83 | NFKB1 (0.59) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL10629636 | 0.83 | NFKB1 (0.52) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL5346373 | 0.83 | CYP19A1 (0.59) | NFKB1KCNH2NFKB2RELAFNTA | |
| SCHEMBL10629608 | 0.83 | CYP19A1 (0.59) | NFKB1KCNH2NFKB2RELAFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474668-B1 | CONVERSION OF DELTA 16-STEROID TO A DELTA 17(20)-20-SILYL ETHER | THE UPJOHN COMPANY (US) | 1993-08-25 | — | — | EP | claimed |