Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 4/20 | 0.33 |
| ▸ | HTR1B | P28222 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522035 | 0.81 | MAPT (0.35) | MAPTHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9522093 | 0.79 | CYP3A4 (0.42) | MAPTHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9521230 | 0.76 | MAPT (0.43) | MAPTHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9520881 | 0.76 | PPARA (0.35) | MAPTHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9522122 | 0.73 | AOC3 (0.50) | MAPTHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL9521646 | 0.72 | S1PR1 (0.50) | S1PR1 | |
| SCHEMBL9521623 | 0.71 | NPC1 (0.44) | MAPTALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL9520118 | 0.71 | ESR1 (0.47) | MAPTHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL14813367 | 0.70 | GRM2 (0.40) | GRM2 | |
| SCHEMBL29502782 | 0.70 | GRM2 (0.40) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5175177-A | 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |