Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30772115 | 0.79 | ESR1 (0.44) | ESR1ESR2MAPTHSD17B10KDM4E | |
| SCHEMBL30772116 | 0.79 | ESR1 (0.44) | ESR1ESR2MAPTHSD17B10KDM4E | |
| SCHEMBL3696821 | 0.79 | ESR1 (0.44) | ESR1ESR2MAPTHSD17B10KDM4E | |
| SCHEMBL4386662 | 0.75 | CASP3 (0.68) | L3MBTL1MAPTHSD17B10KDM4ENPSR1 | |
| SCHEMBL12714322 | 0.74 | ESR1 (0.41) | ESR1ESR2MAPTHSD17B10KDM4E | |
| SCHEMBL2642361 | 0.73 | PDK2 (0.49) | L3MBTL1MAPTHSD17B10KDM4ENPSR1 | |
| SCHEMBL11802995 | 0.72 | ESR1 (0.46) | ESR1ESR2MAPTHSD17B10KDM4E | |
| SCHEMBL18633733 | 0.71 | ESR1 (0.41) | ESR1ESR2MAPTHSD17B10KDM4E | |
| SCHEMBL9523262 | 0.71 | MAPT (0.35) | L3MBTL1MAPTHSD17B10KDM4ENPSR1 | |
| SCHEMBL28591897 | 0.69 | ESR1 (0.40) | ESR1ESR2MAPTHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5175177-A | 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |