Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402115 | 0.81 | MAPK1 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28512961 | 0.78 | BCAT2 (0.53) | PARP1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL7881091 | 0.77 | NPC1 (0.47) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL2542278 | 0.76 | HTT (0.58) | PARP1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL4337078 | 0.75 | HDAC4 (0.53) | KDM4EALDH1A1SMN1; SMN2HPGDMAPT | |
| Hydrochloric Acid SCHEMBL18138748 | 0.75 | MYC (0.49) | PARP1KDM4ENPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL1823813 | 0.75 | HTT (0.57) | PARP1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL4963334 | 0.74 | BCAT2 (0.53) | PARP1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL2855495 | 0.73 | KDM4E (0.55) | PARP1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL2835948 | 0.72 | PARP1 (0.55) | PARP1KDM4ENPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279633-B1 | ANTICONVULSANT AGENTS | ELI LILLY AND COMPANY (US) | 1993-04-07 | — | — | EP | disclosed |
| EP-0279633-A2 | Anticonvulsant agents | ELI LILLY AND COMPANY (US) | 1988-08-24 | — | — | EP | disclosed |