Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523352 | 0.81 | CA2 (0.33) | CA2CA4 | |
| SCHEMBL10513453 | 0.79 | CA2 (0.45) | CA2CA4 | |
| SCHEMBL9525157 | 0.79 | CA2 (0.42) | CA2CA4 | |
| SCHEMBL9522016 | 0.74 | — | — | |
| SCHEMBL8793892 | 0.73 | CA2 (0.39) | CA2CA4 | |
| SCHEMBL10801119 | 0.72 | CA2 (0.48) | CA2CA4 | |
| SCHEMBL10514128 | 0.71 | CA2 (0.51) | CA2CA4 | |
| SCHEMBL10798617 | 0.71 | CA2 (0.38) | CA2CA4 | |
| SCHEMBL10513048 | 0.70 | CA2 (0.54) | CA2CA4 | |
| SCHEMBL8793859 | 0.70 | CA2 (0.57) | CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296879-B1 | SUBSTITUTED AROMATIC SULFONAMIDES AS ANTIGLAUCOMA AGENTS | MERCK & CO. INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4863922-A | Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use | MERCK & CO., INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4824968-A | REMOVING HYDROXYL GROUP WITH SODIUM IODIDE AND DICHLORODIMETHYLSILANE IN ACETONITRILE | MERCK & CO., INC. (US) | 1989-04-25 | — | — | US | disclosed |
| US-4820848-A | Substituted aromatic sulfonamides as antiglaucoma agents | MERCK & CO., INC. (US) | 1989-04-11 | — | — | US | disclosed |
| US-4797413-A | Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use | MERCK & CO., INC. (US) | 1989-01-10 | — | — | US | disclosed |
| EP-0296879-A1 | Substituted aromatic sulfonamides as antiglaucoma agents | MERCK & CO. INC. (US) | 1988-12-28 | — | — | EP | disclosed |