Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28568682 | 0.79 | TSHR (0.50) | TSHRKMT2AMEN1SLC1A1LMNA | |
| SCHEMBL9191996 | 0.79 | TSHR (0.50) | TSHRKMT2AMEN1SLC1A1LMNA | |
| SCHEMBL12534381 | 0.76 | SLC1A1 (0.51) | TSHRKMT2AMEN1SLC1A1LMNA | |
| SCHEMBL7366500 | 0.76 | SLC1A1 (0.51) | TSHRKMT2AMEN1SLC1A1LMNA | |
| SCHEMBL6825006 | 0.74 | L3MBTL1 (0.46) | TSHRKMT2AMEN1SLC1A1LMNA | |
| SCHEMBL6983467 | 0.74 | — | — | |
| SCHEMBL9405314 | 0.74 | — | — | |
| SCHEMBL28823934 | 0.72 | — | — | |
| SCHEMBL5063145 | 0.72 | TSHR (0.52) | TSHRKMT2AMEN1SLC1A1LMNA | |
| SCHEMBL9190278 | 0.69 | SLC1A1 (0.53) | TSHRKMT2AMEN1SLC1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390693-B1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1993-08-25 | — | — | EP | claimed |