Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512165 | 0.70 | CA2 (1.00) | CA2 | |
| SCHEMBL2351369 | 0.70 | CA2 (0.54) | CA2 | |
| SCHEMBL10513904 | 0.70 | CA2 (0.54) | CA2 | |
| SCHEMBL12495117 | 0.70 | CA2 (0.54) | CA2 | |
| SCHEMBL9654181 | 0.70 | CA2 (0.40) | CA2 | |
| SCHEMBL10511944 | 0.68 | CA2 (0.82) | CA2 | |
| SCHEMBL9652934 | 0.67 | CA2 (0.38) | CA2 | |
| SCHEMBL9739615 | 0.65 | CA2 (0.48) | CA2 | |
| SCHEMBL9522485 | 0.63 | CA2 (0.52) | CA2 | |
| SCHEMBL3930475 | 0.62 | CA2 (0.45) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296879-B1 | SUBSTITUTED AROMATIC SULFONAMIDES AS ANTIGLAUCOMA AGENTS | MERCK & CO. INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4863922-A | Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use | MERCK & CO., INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4824968-A | REMOVING HYDROXYL GROUP WITH SODIUM IODIDE AND DICHLORODIMETHYLSILANE IN ACETONITRILE | MERCK & CO., INC. (US) | 1989-04-25 | — | — | US | disclosed |
| US-4820848-A | Substituted aromatic sulfonamides as antiglaucoma agents | MERCK & CO., INC. (US) | 1989-04-11 | — | — | US | disclosed |
| US-4797413-A | Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use | MERCK & CO., INC. (US) | 1989-01-10 | — | — | US | disclosed |
| EP-0296879-A1 | Substituted aromatic sulfonamides as antiglaucoma agents | MERCK & CO. INC. (US) | 1988-12-28 | — | — | EP | disclosed |