Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523646 | 1.00 | CYP1B1 (0.56) | CYP1B1MAOBKMT2AMEN1APP | |
| SCHEMBL7922516 | 0.90 | CYP1B1 (0.64) | CYP1B1MAOBKMT2AMEN1BCHE | |
| SCHEMBL6908275 | 0.90 | CYP1B1 (0.64) | CYP1B1MAOBKMT2AMEN1BCHE | |
| SCHEMBL10744598 | 0.87 | KMT2A (0.64) | CYP1B1MAOBKMT2AMEN1BCHE | |
| SCHEMBL10744603 | 0.87 | KMT2A (0.64) | CYP1B1MAOBKMT2AMEN1BCHE | |
| SCHEMBL9589678 | 0.86 | MAOB (0.64) | MAOBKMT2AMEN1APPALDH1A1 | |
| SCHEMBL9589680 | 0.86 | MAOB (0.64) | MAOBKMT2AMEN1APPALDH1A1 | |
| SCHEMBL10398597 | 0.86 | MAOB (0.58) | MAOBKMT2AMEN1APPBCHE | |
| SCHEMBL10670204 | 0.85 | MAOB (0.51) | MAOBKMT2AMEN1APPALDH1A1 | |
| SCHEMBL10398009 | 0.85 | FBP1 (0.47) | MAOBKMT2AMEN1APPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354583-B1 | DC-88A derivatives | KYOWA HAKKO KOGYO KK (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5117006-A | DC-88A DERIVATIVES USEFUL AS ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| US-5084468-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0354583-A1 | DC-88A derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |