Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654395 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL31384424 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HPGDTSHRMAPTKMT2A | |
| SCHEMBL6652362 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDTSHR | |
| SCHEMBL1523175 | 0.80 | TSHR (0.53) | ALDH1A1HPGDTSHRHMGB1MAPT | |
| SCHEMBL8708824 | 0.80 | TSHR (0.49) | ALDH1A1HPGDTSHRHSP90AA1HMGB1 | |
| SCHEMBL8708820 | 0.80 | TSHR (0.49) | ALDH1A1HPGDTSHRHSP90AA1HMGB1 | |
| SCHEMBL25274950 | 0.79 | TSHR (0.47) | ALDH1A1HPGDTSHRHSP90AA1HMGB1 | |
| SCHEMBL7291481 | 0.79 | ALDH1A1 (0.72) | ALDH1A1HPGDTSHRMAPTKMT2A | |
| SCHEMBL25231628 | 0.79 | HMGB1 (0.47) | ALDH1A1HPGDTSHRHSP90AA1HMGB1 | |
| SCHEMBL4369127 | 0.79 | TSHR (0.47) | ALDH1A1HPGDTSHRHSP90AA1HMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523067-A1 | CROP-SELECTIVE HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-20 | — | — | EP | disclosed |
| WO-1991015478-A1 | CROP-SELECTIVE HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-17 | — | — | WO | disclosed |