Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869004 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2DRD1 | |
| SCHEMBL9870055 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2DRD1 | |
| SCHEMBL9527195 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2DRD1 | |
| SCHEMBL9332729 | 0.81 | MEN1 (0.46) | DRD1PTAFR | |
| SCHEMBL10022354 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2DRD1 | |
| SCHEMBL8996127 | 0.79 | PTAFR (0.44) | PTAFR | |
| SCHEMBL7869540 | 0.79 | MEN1 (0.46) | DRD1 | |
| SCHEMBL8996141 | 0.78 | PTAFR (0.42) | SMN1; SMN2DRD1PTAFR | |
| SCHEMBL8996177 | 0.78 | PTAFR (0.53) | SMN1; SMN2DRD1PTAFR | |
| SCHEMBL9524861 | 0.78 | TP53 (0.39) | SMN1; SMN2PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530207-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |