Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329396 | 0.91 | MEN1 (0.46) | MEN1KMT2AMAPTDRD1ROCK2 | |
| SCHEMBL7876035 | 0.87 | ALOX15 (0.48) | MEN1KMT2ATP53ROCK2HSD17B10 | |
| SCHEMBL7873335 | 0.87 | CRBN (0.41) | MEN1KMT2AMAPT | |
| SCHEMBL9559464 | 0.86 | HSD17B10 (0.47) | MEN1KMT2ADRD1ROCK2HSD17B10 | |
| SCHEMBL9384000 | 0.86 | POLB (0.38) | MEN1KMT2AMAPTDRD1TP53 | |
| SCHEMBL9726878 | 0.85 | MAPK1 (0.52) | MAPTTP53HSD17B10 | |
| SCHEMBL9727194 | 0.84 | TP53 (0.46) | MEN1KMT2AMAPTTP53ROCK2 | |
| SCHEMBL9332729 | 0.84 | MEN1 (0.46) | MEN1KMT2ADRD1TP53 | |
| Hydrochloric Acid SCHEMBL9697856 | 0.81 | MEN1 (0.45) | MEN1KMT2ADRD1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9523368 | 0.81 | MEN1 (0.45) | MEN1KMT2ADRD1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306853-B1 | DICARBOXYLIC ESTER DERIVATIVES OF DIHYDROPYRIDINE COMPOUNDS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| EP-1055672-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 2000-11-29 | — | — | EP | disclosed |
| EP-0943615-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1999-09-22 | — | — | EP | disclosed |
| EP-0389189-B1 | Diazepine antiallergy agents | PFIZER LTD (GB) | 1994-05-18 | — | — | EP | disclosed |
| EP-0466711-B1 | DIHYDROPYRIMIDINE ANTIALLERGY AGENTS | PFIZER LTD (GB) | 1993-10-27 | — | — | EP | disclosed |
| EP-0462986-B1 | IMIDAZOPYRIMIDINE ANTIALLERGY AGENTS | Pfizer Limited (GB) | 1993-10-06 | — | — | EP | disclosed |
| US-5248681-A | DIHYDROPYRIDINE ANTIALLERGY AGENTS | PFIZER INC. (US) | 1993-09-28 | — | — | US | disclosed |
| EP-0551291-A1 | THERAPEUTIC (PAF ANTAGONISTS) AGENTS | Pfizer Limited (GB) | 1993-07-21 | — | — | EP | disclosed |
| EP-0548125-A1 | SUBSTITUTED 6,7-DIHYDROIMIDAZO(1,5,4-EF)(1,5)BENZODIAZEPIN-6-ONES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | Pfizer Limited (GB) | 1993-06-30 | — | — | EP | disclosed |
| US-5214044-A | Antiallergens | PFIZER INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | disclosed |
| WO-1990012015-A1 | DIHYDROPYRIDINE ANTIALLERGY AGENTS | PFIZER LIMITED (GB) | 1990-10-18 | — | — | WO | disclosed |
| US-4963560-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1990-10-16 | — | — | US | disclosed |
| WO-1990011281-A1 | DIHYDROPYRIMIDINE ANTIALLERGY AGENTS | PFIZER LIMITED (GB) | 1990-10-04 | — | — | WO | disclosed |
| WO-1990011280-A1 | 1,4-DIHYDROPYRIDINES | PFIZER LIMITED (GB) | 1990-10-04 | — | — | WO | disclosed |
| EP-0389189-A2 | Diazepine antiallergy agents | Pfizer Limited (GB) | 1990-09-26 | — | — | EP | disclosed |
| WO-1990010632-A1 | IMIDAZOPYRIMIDINE ANTIALLERGY AGENTS | PFIZER LIMITED (GB) | 1990-09-20 | — | — | WO | disclosed |
| US-4935430-A | Platelet activating factor antagonists | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| EP-0365140-A1 | 1,4-Dihydropyridine derivatives | Pfizer Limited (GB) | 1990-04-25 | — | — | EP | disclosed |
| EP-0310386-A2 | 4-Aryl-5-carbamoyl-1,4-dihydropyridines | Pfizer Limited (GB) | 1989-04-05 | — | — | EP | disclosed |