Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NMT1 | P30419 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Carbamate SCHEMBL9381190 | 0.93 | HTR2C (0.50) | HTR2CSMN1; SMN2CYP2C19TSHRNMT1 | |
| SCHEMBL28299374 | 0.85 | ALDH1A1 (0.65) | HTR2CSMN1; SMN2TSHRNMT1ALDH1A1 | |
| Benzyl Carbamate SCHEMBL8798115 | 0.85 | ALDH1A1 (0.49) | HTR2CSMN1; SMN2CYP2C19TSHRALDH1A1 | |
| Benzyl Carbamate SCHEMBL8333051 | 0.85 | NMT1 (0.46) | HTR2CSMN1; SMN2CYP2C19TSHRNMT1 | |
| Benzyl Carbamate SCHEMBL3864753 | 0.83 | ALDH1A1 (0.50) | HTR2CSMN1; SMN2CYP2C19TSHRALDH1A1 | |
| Benzyl Carbamate SCHEMBL9379350 | 0.81 | HTR2C (0.46) | HTR2CSMN1; SMN2CYP2C19TSHRALDH1A1 | |
| Benzyl Carbamate SCHEMBL30227887 | 0.80 | ALDH1A1 (0.63) | SMN1; SMN2ALDH1A1SLC6A2SLC6A3LMNA | |
| Benzyl Carbamate SCHEMBL1697 | 0.80 | ALDH1A1 (0.63) | SMN1; SMN2ALDH1A1SLC6A2SLC6A3LMNA | |
| Benzyl Carbamate SCHEMBL30227819 | 0.80 | ALDH1A1 (0.63) | SMN1; SMN2ALDH1A1SLC6A2SLC6A3LMNA | |
| Benzyl Carbamate SCHEMBL10700633 | 0.80 | ALDH1A1 (0.63) | SMN1; SMN2ALDH1A1SLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562042-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1993-09-29 | — | — | EP | disclosed |
| US-5137892-A | Bactericides | ABBOTT LABORATORIES (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1992010191-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1992-06-25 | — | — | WO | disclosed |