Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | YARS1 | P54577 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28267396 | 0.87 | SLC7A5 (0.65) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL638519 | 0.87 | SLC7A5 (0.65) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL4453960 | 0.85 | SLC7A5 (0.67) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL27680265 | 0.85 | SLC7A5 (0.67) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL7109452 | 0.84 | SLC7A5 (0.63) | SLC7A5HDAC8ALPIPKMPTGS1 | |
| SCHEMBL17738628 | 0.84 | SLC7A5 (0.65) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL8012238 | 0.84 | SLC7A5 (0.65) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL11456 | 0.84 | SLC7A5 (0.65) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL18025358 | 0.84 | SLC7A5 (0.65) | SLC7A5TAAR1SLC6A2HDAC8ESR1 | |
| SCHEMBL1253728 | 0.84 | SLC7A5 (0.65) | SLC7A5TAAR1SLC6A2HDAC8ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345248-B1 | USE OF THE ENZYME-COFACTOR NADPH IN THE PREPARATION OF A PHARMACEUTICAL, PHARMACEUTICAL AND PREPARATION THEREOF | Birkmayer, Jörg, Univ.-Prof. DDr. (AT) | 1993-03-31 | — | — | EP | claimed |