Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11575794 | 0.83 | TDP1 (0.52) | TDP1CYP3A4MAPK1TSHRMAPT | |
| SCHEMBL1876519 | 0.83 | CYP3A4 (0.67) | TDP1CYP3A4MAPK1TSHRMAPT | |
| SCHEMBL20360536 | 0.83 | TDP1 (0.58) | TDP1CYP3A4MAPK1TSHRMAPT | |
| SCHEMBL11500572 | 0.81 | TDP1 (0.69) | TDP1CYP3A4MAPK1TSHRMAPT | |
| SCHEMBL11573454 | 0.81 | TDP1 (0.65) | TDP1CYP3A4MAPK1TSHRMAPT | |
| SCHEMBL11494094 | 0.80 | TDP1 (0.63) | TDP1CYP3A4MAPK1TSHRMAPT | |
| Isopropalin SCHEMBL8541202 | 0.79 | TDP1 (0.61) | TDP1CYP3A4MAPK1TSHRMAPT | |
| SCHEMBL11651136 | 0.79 | TDP1 (0.75) | TDP1CYP3A4MAPK1TSHRMAPT | |
| Isopropalin SCHEMBL55296 | 0.79 | TDP1 (0.61) | TDP1CYP3A4MAPK1TSHRMAPT | |
| SCHEMBL11483505 | 0.79 | ALDH3A1 (0.67) | TDP1CYP3A4MAPK1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523067-A1 | CROP-SELECTIVE HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-20 | — | — | EP | disclosed |