Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.60 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.60 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 7/20 | 0.45 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3765284 | 0.83 | F2 (0.43) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL6677573 | 0.80 | GAA (0.36) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL6228820 | 0.80 | CA1 (0.59) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL10754112 | 0.79 | F2 (0.38) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL11379978 | 0.78 | CDC25B (0.44) | F2PRSS1PRSS2PRSS3SMN1; SMN2 | |
| SCHEMBL10438854 | 0.77 | SMN1; SMN2 (0.47) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL30806173 | 0.77 | TSHR (0.56) | CA1CA2SMN1; SMN2TSHRCA9 | |
| SCHEMBL6226409 | 0.77 | NPC1 (0.47) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL9188413 | 0.77 | TSHR (0.56) | CA1CA2SMN1; SMN2TSHRCA9 | |
| SCHEMBL10885567 | 0.76 | CDK2 (0.37) | F2PRSS1PRSS2PRSS3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338424-B1 | N-((6-trifluoromethylpyrimidin-2-yl)-aminocarbonyl)-2-carboalkoxy-benzenesulfonamides, process for their preparation and their use | BASF AG (DE) | 1993-11-24 | — | — | EP | claimed |
| EP-0046626-B1 | SUBSTITUTED BENZENESULFONYL ISOCYANATES AND PREPARATION THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-02-08 | — | — | EP | claimed |
| US-5100459-A | Herbicides, plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| US-5032167-A | Herbicides | BASF (DE) | 1991-07-16 | — | — | US | disclosed |
| EP-0030139-A2 | Herbicidal ureas and isoureas, preparation and use thereof, and compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | disclosed |