Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 7/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791356 | 0.89 | GCGR (0.40) | GCGRADORA2AADORA1PDE3BPDE3A | |
| SCHEMBL9523672 | 0.89 | GCGR (0.40) | GCGRADORA2AADORA1PDE3BPDE3A | |
| SCHEMBL9698112 | 0.83 | GCGR (0.44) | GCGRMAPK14CYP1A2CYP2C19 | |
| SCHEMBL9527126 | 0.80 | GCGR (0.60) | GCGR | |
| SCHEMBL8949603 | 0.79 | GCGR (0.58) | GCGRMAPK14 | |
| SCHEMBL9382441 | 0.78 | GCGR (0.42) | GCGRADORA2AADORA1MAPK14CYP1A2 | |
| SCHEMBL9791355 | 0.77 | HMGCR (0.47) | GCGR | |
| SCHEMBL9523457 | 0.76 | HMGCR (0.48) | GCGR | |
| SCHEMBL9525348 | 0.76 | HMGCR (0.65) | — | |
| SCHEMBL9525358 | 0.76 | HMGCR (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391185-B1 | Substituted 1,8-naphthyridines | BAYER AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| US-5034399-A | Enzyme inhibitors, anticholesterol agents or antilipemic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-23 | — | — | US | disclosed |
| EP-0391185-A1 | Substituted 1,8-naphthyridines | BAYER AG (DE) | 1990-10-10 | — | — | EP | disclosed |