SCHEMBL952431

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL948965	0.88	CHEK1 (0.43)	SCDNTRK1METCHEK1
	SCHEMBL949236	0.87	CHEK1 (0.47)	SCDCHEK1
	SCHEMBL948930	0.87	SCD (0.38)	SCDCACNA1HCACNA1GCACNA1ISMN1; SMN2
	SCHEMBL948498	0.87	SCD (0.47)	SCDSMN1; SMN2MAPTCYP1A2CYP2C9
	SCHEMBL951797	0.86	SCD (0.38)	SCDCACNA1HCACNA1GCACNA1ISMN1; SMN2
	SCHEMBL949298	0.85	CHEK1 (0.44)	SCDCHEK1
	SCHEMBL952011	0.85	CHEK1 (0.49)	SCDCHEK1
	SCHEMBL947663	0.85	CHEK1 (0.48)	SCDNTRK1SCD5CHEK1
	SCHEMBL949059	0.85	CHEK1 (0.46)	SCDNTRK1CHEK1
	SCHEMBL950328	0.83	SMN1; SMN2 (0.39)	SMN1; SMN2MAPTCYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.