Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.41 |
| ▸ | CA2 | P00918 | 13/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10781544 | 0.76 | IAPP (0.53) | CA1CA2CA9CA5ACA4 | |
| SCHEMBL8349565 | 0.75 | CA2 (0.54) | CA1CA2CA9CA5ACA4 | |
| SCHEMBL9526585 | 0.73 | CA1 (0.40) | CA1CA2CA9CA5ACA4 | |
| SCHEMBL10687709 | 0.73 | CA2 (0.44) | CA1CA2CA9CA5AADRB2 | |
| SCHEMBL9523787 | 0.72 | CA1 (0.41) | CA1CA2CA9CA5AADRB2 | |
| SCHEMBL29704117 | 0.72 | CA2 (0.47) | CA1CA2CA9CA5AADRB2 | |
| SCHEMBL623822 | 0.72 | CA2 (0.47) | CA1CA2CA9CA5AADRB2 | |
| SCHEMBL301797 | 0.72 | CA2 (0.47) | CA1CA2CA9CA5ACA4 | |
| SCHEMBL7351477 | 0.71 | CA2 (0.50) | CA1CA2CA9CA5ACA4 | |
| Bicarbonate SCHEMBL27679773 | 0.71 | BID (0.44) | CA1CA2CA9CA5AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575378-A1 | BENZENESULFONYLUREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-12-29 | — | — | EP | claimed |