Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | ADH5 | P11766 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363641 | 0.80 | HPGD (0.68) | LSSCYP3A4BAZ2BHTTHTR2A | |
| Hydrochloric Acid SCHEMBL9368954 | 0.79 | HPGD (0.66) | LSSCYP3A4BAZ2BHTTHTR2A | |
| SCHEMBL8536306 | 0.75 | LSS (0.60) | LSSCYP3A4BAZ2BMAOBHTT | |
| Hydrochloric Acid SCHEMBL5734554 | 0.74 | LSS (0.59) | LSSCYP3A4BAZ2BMAOBHTT | |
| SCHEMBL8536934 | 0.74 | HTR2A (0.60) | LSSCYP3A4BAZ2BHTTHTR2A | |
| SCHEMBL8537654 | 0.73 | HTR2A (0.59) | LSSCYP3A4BAZ2BHTTHTR2A | |
| SCHEMBL20160906 | 0.73 | TDP1 (0.66) | TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8537801 | 0.73 | HTR2A (0.59) | LSSCYP3A4BAZ2BHTTHTR2A | |
| SCHEMBL10329801 | 0.73 | TDP1 (0.65) | TDP1HTTSMN1; SMN2HPGD | |
| SCHEMBL46306 | 0.73 | TDP1 (0.65) | TDP1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537201-A1 | IMIDAZOLYLBENZOYL SUBSTITUTED HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-21 | — | — | EP | disclosed |
| US-5189036-A | Cardiovascular agents; class III antiarrhythmic agents | SCHERING AG (DE) | 1993-02-23 | — | — | US | disclosed |
| WO-1991019709-A1 | IMIDAZOLYLBENZOYL SUBSTITUTED HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-12-26 | — | — | WO | disclosed |