Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524685 | 0.90 | RAB9A (0.39) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9524436 | 0.81 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9524444 | 0.81 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL10375205 | 0.78 | RARB (0.45) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9528039 | 0.78 | RARB (0.45) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9524937 | 0.76 | MEN1 (0.45) | RAB9ASMN1; SMN2HSD17B10KDM4EMAPT | |
| SCHEMBL9525010 | 0.75 | SLC5A2 (0.30) | — | |
| SCHEMBL9239218 | 0.73 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9240109 | 0.72 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL10469343 | 0.72 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351746-B1 | Optically active 1,3-dioxolane derivatives containing a mesogene group in position 4, method for their preparation and their use as doping agents in liquid-crystal mixtures | HOECHST AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0351746-A1 | Optically active 1,3-dioxolane derivatives containing a mesogene group in position 4, method for their preparation and their use as doping agents in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-24 | — | — | EP | disclosed |