Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.82 |
| ▸ | CA4 | P22748 | 4/20 | 0.57 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9680537 | 0.96 | CA1 (0.75) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL7940740 | 0.95 | — | — | |
| Acetic Acid SCHEMBL6427720 | 0.95 | CA1 (0.90) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL3226010 | 0.92 | CA1 (0.69) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL3226007 | 0.92 | CA1 (0.69) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL10353069 | 0.91 | CA1 (0.73) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL8854294 | 0.91 | CA1 (0.73) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL9244992 | 0.91 | CA1 (0.73) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL9600657 | 0.91 | CA1 (0.73) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL1840651 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330195-B1 | PROCESS FOR PRODUCING PYROMELLITIC DIANHYDRIDE AND CATALYST USED IN SAID PROCESS | KAWASAKI STEEL CORPORATION (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-5001100-A | Catalyst used in a process for producing pyromellitic dianhydride | KAWASAKI STEEL CORPORATION (JP) | 1991-03-19 | — | — | US | disclosed |
| US-4925957-A | CATALYTIC OXIDATION OF DURENE | KAWASAKI STEEL CORP. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4612400-A | Autoxidation of bis(ortho dialkyl-phenoxy)benzophenones | THE DOW CHEMICAL COMPANY (US) | 1986-09-16 | — | — | US | disclosed |
| US-4577034-A | Autoxidation of bis(ortho dialkyl-phenoxy)benzophenones | THE DOW CHEMICAL COMPANY (US) | 1986-03-18 | — | — | US | disclosed |
| US-4526984-A | Autoxidation of alkyl-substituted aromatic ethers | THE UPJOHN COMPANY (US) | 1985-07-02 | — | — | US | disclosed |