Acetic Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA2A ADRA2B ADRA2C ADRB2 AGTR1 AVPR1A AVPR1B AVPR2 BDKRB2 CALCR CHRNA3 CHRNB4 ESR1 ESR2 GHSR GNRHR GSC1 HSPA8 MALT1 MC1R MC4R NOS1 NOS2 NOS3 OPRK1 OXTR RAMP1 RAMP2 RAMP3 SCN5A SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 dacA dacB dacC folP ftsI mrcA mrcB mrdA rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	CA1	P00915	2/20	0.69

▸	CA4	P22748	4/20	0.50

▸	FAHD1	Q6P587	1/20	0.40

▸	LMNA	P02545	3/20	0.36

▸	FFAR3	O14843	2/20	0.33

▸	BLM	P54132	2/20	0.33

▸	HDAC3	O15379	1/20	0.33

▸	HDAC1	Q13547	1/20	0.33

▸	HDAC2	Q92769	1/20	0.33

▸	HDAC8	Q9BY41	1/20	0.33

▸	MEN1	O00255	1/20	0.33

▸	LDHA	P00338	1/20	0.33

▸	KMT2A	Q03164	1/20	0.33

▸	TSHR	P16473	1/20	0.33

▸	THPO	P40225	1/20	0.33

▸	LCK	P06239	1/20	0.33

▸	FYN	P06241	1/20	0.33

▸	CA2	P00918	1/20	0.32

▸	CASP1	P29466	1/20	0.32

▸	ALOX15	P16050	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Acetic Acid SCHEMBL3226010	1.00	CA1 (0.69)	CA1CA4FAHD1LMNAFFAR3
Acetic Acid SCHEMBL9680537	0.96	CA1 (0.75)	CA1CA4FAHD1LMNAFFAR3
Acetic Acid SCHEMBL9600657	0.92	CA1 (0.73)	CA1CA4FAHD1LMNAFFAR3
Acetic Acid SCHEMBL9524565	0.92	CA1 (0.82)	CA1CA4FAHD1LMNAFFAR3
Acetic Acid SCHEMBL9681810	0.88	CA1 (0.67)	CA1CA4FAHD1LMNAFFAR3
Acetic Acid SCHEMBL25274010	0.88	CA1 (0.90)	CA1CA4FAHD1LMNAFFAR3
Acetic Acid SCHEMBL7940740	0.88	—	—
Acetic Acid SCHEMBL29744996	0.88	CA1 (0.90)	CA1CA4FAHD1LMNAFFAR3
Acetic Acid SCHEMBL28438944	0.88	CA1 (0.80)	CA1CA4FAHD1LMNAFFAR3
Acetic Acid SCHEMBL4905553	0.88	CA1 (0.80)	CA1CA4FAHD1LMNAFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20100056750-A1	PROCESS FOR THE SYNTHESIS OF HALOGENATED AROMATIC DIACIDS	E. I. DU PONT DE NEMOURS AND COMPANY	2010-03-04	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20100056750-A1	PROCESS FOR THE SYNTHESIS OF HALOGENATED AROMATIC DIACIDS	TYR, DDC, DDT	CA1 2604/4885CA4 240/4885FAHD1 1887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.