Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9525862 | 0.99 | SLC2A1 (0.69) | SLC2A1CYP1A2CD274KDM4EALDH1A1 | |
| SCHEMBL9779055 | 0.89 | SLC2A1 (0.69) | SLC2A1CYP1A2CD274 | |
| SCHEMBL9535866 | 0.88 | SLC2A1 (0.89) | SLC2A1CD274 | |
| SCHEMBL9778877 | 0.84 | SLC2A1 (0.79) | SLC2A1 | |
| SCHEMBL9536774 | 0.83 | SLC2A1 (1.00) | SLC2A1 | |
| SCHEMBL9538640 | 0.82 | SLC2A1 (0.58) | SLC2A1CYP1A2ALDH1A1HPGD | |
| SCHEMBL9537194 | 0.81 | SLC2A1 (0.72) | SLC2A1CYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL10545553 | 0.80 | SLC2A1 (0.55) | SLC2A1CYP1A2CD274KDM4EALDH1A1 | |
| SCHEMBL9526583 | 0.80 | SLC2A1 (0.56) | SLC2A1CYP1A2CD274 | |
| Hydrochloric Acid SCHEMBL10546310 | 0.79 | SLC2A1 (0.54) | SLC2A1CYP1A2CD274KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183439-A2 | Polycyclic compounds, their preparation and use and formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-06-04 | — | — | EP | claimed |
| EP-0183439-B1 | POLYCYCLIC COMPOUNDS, THEIR PREPARATION AND USE AND FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-02-03 | — | — | EP | disclosed |
| US-5075455-A | Microbiocides, antitumor agents | BURROUGHS WELLCOME CO. (US) | 1991-12-24 | — | — | US | disclosed |
| US-5049581-A | Dibenzofurans having anti-tumor activity | BURROUGHS WELLCOME CO. (US) | 1991-09-17 | — | — | US | disclosed |
| US-5017600-A | Antitumor | BURROUGHS WELLCOME CO. (US) | 1991-05-21 | — | — | US | disclosed |
| US-5008286-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1991-04-16 | — | — | US | disclosed |
| US-4970227-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1990-11-13 | — | — | US | disclosed |
| US-4965285-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1990-10-23 | — | — | US | disclosed |
| US-4866070-A | ANTITUMOR AGENT | BURROUGHS WELLCOME CO. (US) | 1989-09-12 | — | — | US | disclosed |
| EP-0183439-A2 | Polycyclic compounds, their preparation and use and formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-06-04 | — | — | EP | disclosed |