Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538641 | 0.75 | CYP19A1 (0.46) | HSD17B10ALDH1A1L3MBTL1CYP3A4DRD3 | |
| SCHEMBL9523337 | 0.73 | CYP19A1 (0.55) | CYP3A4ADORA3CYP1A2CYP2D6MEN1 | |
| SCHEMBL11540241 | 0.72 | CYP19A1 (0.51) | HSD17B10ALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL9015372 | 0.69 | HDAC4 (0.68) | CTSDHDAC4HDAC7HDAC5ALDH1A1 | |
| SCHEMBL9059780 | 0.68 | LMNA (0.53) | CTSDHDAC4HDAC7HDAC5ALDH1A1 | |
| SCHEMBL27887015 | 0.68 | HDAC4 (0.50) | CTSDHDAC4HDAC7HDAC5ALDH1A1 | |
| SCHEMBL27828567 | 0.66 | HDAC4 (0.48) | CTSDHDAC4HDAC7HDAC5ALDH1A1 | |
| SCHEMBL11871960 | 0.66 | HDAC4 (0.48) | CTSDHDAC4HDAC7HDAC5ALDH1A1 | |
| SCHEMBL4385009 | 0.65 | HDAC4 (0.47) | HSD17B10CTSDHDAC4HDAC7HDAC5 | |
| SCHEMBL3555929 | 0.65 | HSD17B10 (0.58) | HSD17B10HDAC4HDAC7HDAC5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396769-B1 | AZOXY COMPOUND | KOWA CO. LTD. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5093480-A | Fungicides | KOWA COMPANY, LTD. (JP) | 1992-03-03 | — | — | US | disclosed |