Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.61 |
| ▸ | GSK3A | P49840 | 2/20 | 0.61 |
| ▸ | GSK3B | P49841 | 2/20 | 0.61 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.61 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.61 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.61 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522322 | 0.94 | LMNA (0.58) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9523388 | 0.94 | LMNA (0.64) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9617588 | 0.89 | PIM1 (0.77) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9693620 | 0.89 | PIM1 (0.77) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9617590 | 0.89 | PIM1 (0.77) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9522195 | 0.89 | LMNA (0.65) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9522159 | 0.88 | PIM1 (0.59) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9523675 | 0.88 | PIM1 (0.59) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10569529 | 0.88 | LMNA (0.60) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9559230 | 0.87 | PIM1 (0.60) | PIM1GSK3AGSK3BPIM3PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249043-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4843070-A | BACTERIDCIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0249043-A2 | Quinolinecarboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1987-12-16 | — | — | EP | disclosed |