Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525021 | 0.88 | ABCB1 (0.40) | ABCC9ABCB1 | |
| SCHEMBL9525728 | 0.87 | ABCB1 (0.39) | ABCC9ABCB1 | |
| SCHEMBL9525704 | 0.87 | ABCB1 (0.39) | ABCC9ABCB1 | |
| SCHEMBL9525034 | 0.86 | ABCC9 (0.40) | ABCC9ABCB1 | |
| SCHEMBL8174399 | 0.85 | ABCB1 (0.40) | ABCC9ABCB1 | |
| SCHEMBL8174728 | 0.85 | ABCB1 (0.40) | ABCC9ABCB1 | |
| SCHEMBL8174878 | 0.85 | ABCB1 (0.40) | ABCC9ABCB1 | |
| SCHEMBL9527718 | 0.85 | ABCC9 (0.39) | ABCC9ABCB1 | |
| SCHEMBL9525708 | 0.83 | ABCC9 (0.39) | ABCC9ABCB1 | |
| SCHEMBL9523998 | 0.81 | ABCC9 (0.43) | ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298452-B1 | 2H-1-BENZOPYRANE DERIVATIVES SUBSTITUTED IN POSITION 4 BY ARYL OR N-HETEROARYL | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-30 | — | — | EP | claimed |
| US-5118694-A | Hypotensive agents; treatment for cardiovascular and muscular disorders | HOFFMANN-LA ROCHE INC. (US) | 1992-06-02 | — | — | US | disclosed |
| US-4971982-A | HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS, SMOOTH MUSCLE DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1990-11-20 | — | — | US | disclosed |