Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525531 | 0.94 | MAPT (0.52) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL9525482 | 0.92 | MEN1 (0.55) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL9525714 | 0.88 | MEN1 (0.57) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL9525184 | 0.88 | MAPT (0.51) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL9525837 | 0.85 | MAPT (0.48) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL9525576 | 0.83 | TSHR (0.45) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL9525216 | 0.82 | MAPT (0.43) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL9528120 | 0.82 | MEN1 (0.52) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL9524407 | 0.81 | MAPK1 (0.45) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL9525298 | 0.81 | MAPT (0.51) | MEN1KMT2AMAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |