Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525216 | 0.95 | MAPT (0.43) | TSHRPOLBNPSR1HSD17B10ALDH1A1 | |
| SCHEMBL9524407 | 0.95 | MAPK1 (0.45) | TSHRPOLBNPSR1HSD17B10ALDH1A1 | |
| SCHEMBL9524189 | 0.91 | MEN1 (0.49) | TSHRPOLBNPSR1HSD17B10ALDH1A1 | |
| SCHEMBL9525343 | 0.91 | ALDH1A1 (0.44) | TSHRPOLBNPSR1HSD17B10ALDH1A1 | |
| SCHEMBL9526042 | 0.87 | TRPV1 (0.47) | TSHRPOLBNPSR1HSD17B10ALDH1A1 | |
| SCHEMBL9525302 | 0.87 | TRPV1 (0.47) | TSHRPOLBNPSR1HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9524285 | 0.84 | KDM4E (0.41) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9525186 | 0.83 | MEN1 (0.53) | TSHRPOLBNPSR1HSD17B10ALDH1A1 | |
| SCHEMBL9524021 | 0.83 | MEN1 (0.44) | TSHRPOLBNPSR1HSD17B10ALDH1A1 | |
| SCHEMBL9525531 | 0.82 | MAPT (0.52) | TSHRALDH1A1MAPTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |