SCHEMBL9525263

SCHEMBL9525263

Cc1nc2cnccc2n1-c1ccc(C(O)Cc2ccccn2)cc1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9524455 0.80 DRD1 (0.43) DRD1
SCHEMBL9869013 0.79 MAPK1 (0.49) DRD1
SCHEMBL9869414 0.78 DRD1 (0.42) DRD1
SCHEMBL10022354 0.75 SMN1; SMN2 (0.55) DRD1
SCHEMBL540767 0.75 MAPK1 (0.67) DRD1
SCHEMBL7774816 0.72 DRD1 (0.49) DRD1
SCHEMBL9335272 0.72 DRD1 (0.51) DRD1
SCHEMBL9525557 0.72 MAPK1 (0.51) DRD1
SCHEMBL10054042 0.72 DRD1 (0.53) DRD1
SCHEMBL9869004 0.71 SMN1; SMN2 (0.52) DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530207-A1 IMIDAZOPYRIDINE PAF ANTAGONISTS Pfizer Limited (GB) 1993-03-10 EP disclosed
WO-1991017162-A1 IMIDAZOPYRIDINE PAF ANTAGONISTS PFIZER LIMITED (GB) 1991-11-14 WO disclosed