Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL540767 | 0.85 | MAPK1 (0.67) | MAPK1HTTDRD1SMN1; SMN2KDM4E | |
| SCHEMBL10022354 | 0.82 | SMN1; SMN2 (0.55) | DRD1SMN1; SMN2 | |
| SCHEMBL9869004 | 0.81 | SMN1; SMN2 (0.52) | DRD1SMN1; SMN2 | |
| SCHEMBL9524455 | 0.80 | DRD1 (0.43) | DRD1SMN1; SMN2 | |
| SCHEMBL9524668 | 0.80 | HSD17B10 (0.55) | MAPK1HTTSMN1; SMN2 | |
| SCHEMBL9525263 | 0.79 | DRD1 (0.42) | DRD1 | |
| SCHEMBL9335272 | 0.79 | DRD1 (0.51) | MAPK1HTTDRD1 | |
| SCHEMBL9525557 | 0.79 | MAPK1 (0.51) | MAPK1HTTDRD1ATM | |
| SCHEMBL9868648 | 0.79 | MAPK1 (0.51) | MAPK1HTTDRD1ATM | |
| SCHEMBL10054042 | 0.79 | DRD1 (0.53) | MAPK1HTTDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |